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University of California - San Diego

  • Adam Feist, UCSD / DTU

Adaptive Laboratory Evolution (ALE) can be used to obtain useful strains for biotechnology applications. A complete platform containing automation, bioinformatics, and biological selection systems can be used to replace the design and build steps in the rational strain engineering process. This talk will describe the different parts of this platform and current use cases applying it to strain construction goals. Demonstrations of advanced biological selection systems will be highlighted to show how ALE can be utilized to obtain production strains for a wide set of products and for focusing selective pressures on targeted enzymatic steps. An additional specific focus will be to highlight the advantage of having a bioinformatics pipeline and mutation database (i.e., biological parts list) integrated into the platform. We are looking for partners for collaborative projects or contract research to further demonstrate the utility of the ALE technology platform for industrial applications.

  • Date:Tuesday, July 9
  • Time:1:15 PM - 1:30 PM
  • Location:317
  • Session Type:Company and Technical Presentation
  • BIO Track:Advances in Genome Editing and Genomics
Adam Feist